Efficacy of needle-free administration of recombinant human growth hormone in adults with growth hormone deficiency
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چکیده
منابع مشابه
Efficacy and Safety of Sustained-Release Recombinant Human Growth Hormone in Korean Adults with Growth Hormone Deficiency
PURPOSE The administration of recombinant human growth hormone in adults with growth hormone deficiency has been known to improve metabolic impairment and quality of life. Patients, however, have to tolerate daily injections of growth hormone. The efficacy, safety, and compliance of weekly administered sustained-release recombinant human growth hormone (SR-rhGH, Declage™) supplement in patients...
متن کاملEfficacy of growth hormone therapy in adults with childhood-onset growth hormone deficiency
PURPOSE Growth hormone (GH) plays a key role in the regulation of body composition, lipid metabolism, and quality of life in adults with GH deficiency (GHD). This study investigated changes in laboratory findings and body composition after GH recommencement for adult GHD and analyzed correlation between GH interruption period and endocrine or anthropometric parameters. METHODS A total of 45 p...
متن کاملGrowth hormone replacement therapy in adults with growth hormone deficiency; thrice weekly low dose administration.
Recent reports on growth hormone (GH) therapy have shown that GH has various beneficial effects in GH deficient adults. In most of these studies, GH was administered daily. Because GH is still expensive and has to be delivered by subcutaneous injection, we studied the 6-month therapeutic effects of thrice weekly GH injection therapy and compared it with daily therapy. Twenty eight adult patient...
متن کاملEffects of recombinant human growth hormone therapy on bone mineral density in adults with growth hormone deficiency: a meta-analysis.
OBJECTIVE GH deficiency is associated with decreased bone mineral density (BMD) and increased fracture risk. Because the effects of recombinant human GH (rhGH) therapy on BMD and bone mineral content have not been systematically investigated, we conducted a meta-analysis of pertinent studies. DESIGN A thorough search of the literature (MEDLINE, EMBASE, and the Cochrane Register) was performed...
متن کاملTreatment of growth hormone deficiency in adults.
BACKGROUND The Growth Hormone Research Society held a Consensus Workshop in Sydney, Australia, in March 2007 to review advances in the management of growth hormone (GH) deficiency in adults and to update consensus recommendations. OBJECTIVE This short review summarizes key background information presented at the workshop and the consensus recommendations that followed. CONCLUSIONS The benef...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2006
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.2006.02585.x